Tuesday, August 24, 2010

Another 'miracle' cancer drug proves to be a dud...

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In Today's Issue

24 August 2010

  • Unsightly hair gone in 50 seconds
  • Another 'miracle' cancer drug proves to be a dud...

  • Discover the secret new science that pulses pain away


NO MORE UNSIGHTLY, UNWANTED HAIR...



Imagine no pain, no mess, no allergic skin reactions, no cuts and nicks - just silky smooth skin up to 10 times cheaper than normal treatments...

Discover the amazing new technology that gives you professional-grade hair removal without visiting a clinic or salon. It also inhibits hair re-growth and reduces hair density by 64%...

Read the full report on this new technology, here

Another 'Miracle' Cancer Drug Proves to be a Dud...

Dear Reader,

How do you completely botch the approval of a cancer drug and put thousands of desperate patients at increased risk of death while wasting their money?

The American Food and Drug Administration (FDA) and Wyeth have kindly given us a master class in All the Wrong Moves.

First, you develop a drug that promises to be a genuine lifesaver. That was the hype, anyway, back in 2000 when Wyeth asked the FDA to give accelerated approval to Mylotarg.

Quick turn-around

You've probably never heard of Mylotarg because its use is so specific. It's designed to treat a relatively rare type of blood cancer called acute myeloid leukaemia (AML), which occurs mostly in people over the age of 60.

Early tests suggested that Mylotarg use might improve remission rate, and increase overall survival by a few months.

So the FDA gave the drug accelerated approval, but only for patients who had suffered a first relapse of AML and weren't eligible for other chemotherapies. And as with any drug approved on the fast-track programme, Wyeth was required to mount further research.

And this is where things started to go off the rails.

It took Wyeth four years to begin the follow-up Mylotarg study. Four deadly years.

Fast forward...

Wyeth is no more. They were purchased by Pfizer in 2009. But the Mylotarg study they started years ago continued.

Until recently.

One full decade after Mylotarg's hasty approval, Pfizer abruptly stopped the study and took the drug off the market for two reasons:

1) Mylotarg use showed no benefit, and

2) Compared to patients who used standard therapy, it appeared that patients who used standard therapy plus Mylotarg were FOUR TIMES more likely to die during the study!

Meanwhile, this dangerous, poorly-studied drug made millions for Wyeth and Pfizer.

Business Week reports that the sales of Mylotarg in the first quarter of this year were nearly $9 million. But only about 2,500 patients have been using Mylotarg each year.

Meaning, each patient paid more than $14,000 for the required two injections of a drug that doesn't work and might be fatal.

Now, by Big Pharma standards, $14,000 is nothing. That's just walking around money. That's hardly enough to buy off a politician.

But for most patients and their families, a $14,000 medical bill is a serious hardship. Nevertheless, you can be sure that many families who trusted the FDA were plunged into debt or raided their life savings to give their loved one every chance to live, based entirely on Mylotarg's status as a promising miracle drug.

Ah well, this experience goes under "lessons learned," right? As one FDA official pointed out, follow-up trials for fast-tracked drugs should probably be planned and "if possible" already underway when the application is submitted.

Hmmm, it seems like that would have been a really obvious detail to address TEN YEARS AGO!

Continues below...

*Highly Recommended*


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...and another thing

If you want to strengthen bones without drug side effects, some HSI members have a suggestion for that...

After I sent you a recent e-mail about the dangers of osteoporosis drugs, I received several messages from readers about strontium, an important mineral that can actually increase retention of calcium.

Nancy: "You absolutely MUST have strontium included in the mix for bone building."

Jan agrees, noting that strontium reversed her osteoporosis problems.

Jan: "I took 680mg per day for 10 months. I now take 340mg of Strontium Citrate for maintenance. It's important to take strontium & calcium separately, so I take one in the morning & divide the (1000mg) calcium/magnesium (500mg) in the evening."

It's almost as if Jan has been reading Dr. Spreen's mind (or maybe one of his books).

Dr. Spreen: "Dr. Ward Dean, reports that studies of the use of strontium show it to be safe in doses up to 1.7 grams/day, though effective supplemental use of the mineral nutrient tends to be optimized at around 680 milligrams, with lower doses also being effective for osteoporosis (and even cavities).

"It should be noted that its absorption is inhibited when combined with calcium, and the mineral is best absorbed when taken on an empty stomach (one of the few nutrients other than amino acids in which that tends to be true)."


Strontium has been proven to increase bone mineral density, with an important additional benefit. In a study from the Mayo clinic, more than 80 per cent of osteoporosis patients reported significant pain reduction while using strontium.

To Your Good Health,

Jenny Thompson
HSI Director


P.S. This month's Health Sciences Institute (HSI) newsletter will tell you how a cutting-edge herbal formula can finally free you from chronic pain. You'll also discover how to put a stop to the misery of hair loss with a natural formula that can help you retain your hair from the inside out. Plus we'll give you full details about the breakthrough remedy that provides a vital defence against sun-related skin damage.

All new members who sign up to the Health Sciences Institute will receive the latest issue of HSI along with a FREE encyclopaedia, HSI's 100 Greatest Underground Cures... Soon you'll discover why our premium members believe HSI is the ultimate resource for anyone seeking a better, newer solution to their health problems. problems.

Click here for full details.
Sources:

"FDA: Pfizer Voluntarily Withdraws Cancer Treatment Mylotarg from U.S. Market" FDA News Release, 6/21/10, fda.gov

"Pfizer Withdraws Drug After Deaths, No Proven Benefit" Catherine Larkin, Business Week, 6/21/10, businessweek.com

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