Saturday, March 5, 2011

About Alzheimer's Disease: Major Theories of Alzheimer's Disease

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Alzheimer's Disease

Symptoms / Diagnosis



From Andrew Rosenzweig, MD, your Guide to Alzheimer's Disease
As we're now several years past the 100th anniversary of Dr. Alois Alzheimer's discovery of the disease that bears his name, we seem to be less and less sure of what actually causes Alzheimer's disease. Fortunately there is much that we do know about it, and this week's newsletter focuses on the major theories that have arisen to explain the causes of Alzheimer's disease.

Amyloid Cascade Hypothesis of Alzheimer's Disease
Of all the major theories of Alzheimer's disease, the one given most credibility by scientists and Alzheimer's researchers is the Amyloid Cascade Hypothesis... Read more

Oligomers in Alzheimer's Disease
The amyloid cascade hypothesis argues that it is the oligomers made up of 2, 3, or more beta-amyloid subunits that exert the toxic effects of Alzheimer's disease, causing the very early cognitive deficits that occur.... Read more

Mitochondrial Cascade Hypothesis of Alzheimer's Disease
The mitochondrial cascade hypothesis proposes that the changes that occur in mitochondrial functioning as we age actually cause the key brain changes that wreak havoc in Alzheimer's disease... Read more

What Causes Alzheimer's Disease?
One theory about plaques and tangles is that is that they block nerve cells' ability to communicate with each other, making it difficult for the cells to survive....Read more


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This newsletter is written by:
Andrew Rosenzweig, MD
Alzheimer's Disease Guide
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